1. < Breast Cancer

Is anyone on PHESGO?

Posted by varsha08 @varsha08, May 17 10:21am

I was diagnosed with HER2+ and ER PR Negative. After 6 initial chemos, I have been on Perjeta and Herceptin for last 4 years. Now it is PHESGO. Every three weeks. I am able to tolerate it but is bothered by Neuropathy in my hands and feet. Is there anyone going through similar treatment? Or suffering from chemo induced neuropathy?
My oncologist says Perjeta can induce neuropathy only in 8% of the patients! I seem to be a part of that 8%.
I want to know if anyone’s neuropathy went away after the chemos were stopped??Thank you.

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Moderator
Colleen Young, Connect Director | @colleenyoung | May 17 8:07pm

@varsha08, I believe that @vtn has experience with Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) and can share more.

I'm sorry to hear that the new medication is exacerbating the neuropathy. How many treatments have you had so far and how many will you be getting?

REPLY
1 reply
varsha08 | @varsha08 | May 17 8:48pm
In reply to @colleenyoung "@varsha08, I believe that @vtn has experience with Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) and can share..." + (show)
@colleenyoung

@varsha08, I believe that @vtn has experience with Phesgo (pertuzumab, trastuzumab, and hyaluronidase-zzxf) and can share more.

I'm sorry to hear that the new medication is exacerbating the neuropathy. How many treatments have you had so far and how many will you be getting?

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Colleen Young, thank you for your response.
My first chemo was in Feb 2020 using Taxotere + Perjeta + Herceptin. After 6 chemos which ended in June 2020, I am on targeted therapy every three weeks using Perjeta and Herceptin till date and will be continuing till I become immune to it. So to answer your question, how many, more than 70 till date and will go on. The oncologist said they will change the drugs then. In short I am supposed to be on targeted therapy all my life!

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maggieb892 | @maggieb892 | May 18 4:16pm

I had invasive lobular HER 2 + hormone negative breast cancer (stage2). My treatment seems different than yours. 12 wks of Taxol with Perjeta and herceptin every 3wks. Then a mastectomy, radiation and more chemo (Kadcyla) which included herceptin. Treatment began 6/21 and ended 8/22.

I believe that there are several accepted treatment modalities. Options may be different in small cancer centers than in larger centers. Our age, overall health, stage of our cancer also enter into the decision for treatment.

I did develop neuropathy in my feet. It was not debilitating and didn't get any worse. It occasionally bothers me when I'm in bed and trying to sleep.

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1 reply
varsha08 | @varsha08 | May 18 4:33pm
In reply to @maggieb892 "I had invasive lobular HER 2 + hormone negative breast cancer (stage2). My treatment seems different..." + (show)
@maggieb892

I had invasive lobular HER 2 + hormone negative breast cancer (stage2). My treatment seems different than yours. 12 wks of Taxol with Perjeta and herceptin every 3wks. Then a mastectomy, radiation and more chemo (Kadcyla) which included herceptin. Treatment began 6/21 and ended 8/22.

I believe that there are several accepted treatment modalities. Options may be different in small cancer centers than in larger centers. Our age, overall health, stage of our cancer also enter into the decision for treatment.

I did develop neuropathy in my feet. It was not debilitating and didn't get any worse. It occasionally bothers me when I'm in bed and trying to sleep.

Jump to this post

Thank you Maggieb for responding. You are right. Mine was stage 4. MBC spread to lymph nodes and liver. That is the reason they say targeted therapy for life.

Wish you the very best and forever good health!

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