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DiscussionHesitant to begin drug treatment for my osteoporosis
Osteoporosis & Bone Health | Last Active: Oct 20 10:56am | Replies (73)Comment receiving replies
Replies to "Good evening @windyshores, Do you know where the information about negative cancer presence with Forteo and..."
@artscaping the lifting of the black box warning and extension of treatment duration for Forteo is all over the Internet. Sorry I would have posted sources but it is pretty common knowledge at this point though old info is still online and confusing.
As a quick example of sources: https://www.ccjm.org/content/88/9/489
Here is a more detailed study review:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9465003/
some quotes:
"No cases of osteosarcoma were observed in the clinical trials of patients treated with teriparatide"
"These studies showed no increase in osteosarcoma in patients using teriparatide compared with unexposed groups, as well as to the expected population‐based background incidence of the disease. Based on this real‐world evidence and the totality of data collected from postmarketing use and other clinical investigations, the label was updated in 2020. The changes included addition of information from large observational studies using real‐world evidence, removal of the boxed warning, and a revision of the 2‐year lifetime limitation."
It is also in Keith McCormick's book "Great Bones," and two of my doctors have told me this as well. Several others have posted on these changes on Connect.