Bioidentical hormones for osteoporosis

I don’t know if this will help, but yesterday, I received my second dose of estradiol backslash testosterone pellets. After my first dose, I felt terrific. My whole mood was so light. It was very shocking to me this time. He did go up in strength from 37.5 to 50. The average dosing is 100 for a woman in post menopause; my
Bone marker numbers are in the normal range. I have used cream bioidentical hormones for 20 years and decided to switch to the pellets because they deliver more testosterone to the bones. When I get my DEXA scan February I will see if it was worth it With all the side effects of the drugs I really wanted to try this first. It is an individual decision, but I feel really good about it. I will have my Blood done in August before I go for my next appointment. If you do decide on hormone therapy, please find a specialist….mainstream doctor. don't know much about this treatment. I also take progesterone in a pill form. I hope this helps.

Yes

Have you been taking them at the same time for very long?

4 weeks 🙂

@andreamayo which two meds did you take together, and for what reason, if you don’t mind sharing? Thanks!

I'm curious about this too.

From what I’ve learned, estradiol levels for bone protection are usually discussed in ranges, not strict cutoffs, because every woman absorbs transdermal estrogen differently.
For maintaining bone density, many menopause specialists note that serum estradiol levels around 40–60 pg/mL are often sufficient for most women. For women trying to increase bone density, especially in early osteoporosis, levels closer to 60–80 pg/mL (sometimes slightly higher) are associated with more bone-building activity. These numbers are based on clinical observations rather than official guidelines, so they’re best viewed as general targets.
I currently use a 0.05 estradiol patch, and my most recent estradiol level was 60, which falls into the “maintenance” range. Patch absorption varies a lot between individuals, so the same dose can lead to different blood levels in different people.
There is also emerging evidence that testosterone, at physiologic female doses, may provide additional support for bone density, muscle strength, and fall prevention when used together with estradiol. I'm using a testosterone gel, 5 mg a day.
Many clinicians do combine estradiol with osteoporosis medications (like bisphosphonates or others) when someone is in the early stages of osteoporosis. Estrogen helps stabilize or rebuild bone, while osteoporosis drugs work through different mechanisms, so the combination can sometimes be more effective.
I think, if someone has osteopenia or early osteoporosis, a higher-dose patch may help raise estradiol levels into the bone-building range, but it’s very individual.