Hi. I saw your comment @ripley, and understand exactly what you're trying to do. I have moved from 80 mg to 60 mg (very short term) to 40 to 20 to 10mg, using 10 and 20 every other day. Did that for a couple years, and finally was on 10 mg/daily for the last year when my PCP said why not just try Pepcid 20 twice a day, like you did. So far, so good. I'm not sure what you mean by not being successful, but i'm guessing we all have different diagnoses here and it is hard for one person to recommend to another what to do without being a doctor, and without knowing if we have the same symptoms. If your doctor says it's ok to try again, have you considered 40mg in morning and 20mg at night? Or even 40mg twice a day? It sounds like a lot but at least you'd be off pantroprazole and wouldn't have the osteoporosis concern.