← Return to Second opinion for husband's stage 4A prostate cancer? And update

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@northoftheborder

(layperson, again)

This study is pretty old now — radiation therapy, surgical techniques, and pharmaceutical treatments have all advanced massively in 20–25 years — but for *localised* prostate cancer (below stage 4), it found no significant difference in 10-year overall survival among patients who received radiation, surgery, or active surveillance.

https://www.nejm.org/doi/10.1056/NEJMoa1606220

As far as I know, there's still no major evidence that surgery gives a better survival outcome than radiation at any stage — that's what my onco team (researchers who teach at a med school) told me — but each approach comes with a different collection of potential side-effects, and that's probably where you need to focus. And your partner may end up with radiation after a prostatectomy anyway, since their cancer has already escaped the prostate.

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Replies to "(layperson, again) This study is pretty old now — radiation therapy, surgical techniques, and pharmaceutical treatments..."

You are so correct. At 75 they said RT/ADT would suffice. Prostatectomy would result in same outcome. No difference. I’m < .01 PSA 18 months down the road. Two pelvic lymph nodes were affected. Also had it in seminal vessels. You won’t believe me but I felt the cancer fall off the wall of the seminal vessels in bed last week. It was dead- no more testosterone to feed it. Thru the process of phagocytosis the body will destroy this dead tissue. That’s my opinion only, just as me eating mushrooms keeps my PSA at 0. Lol. Hope you enjoyed my info???