← Return to Hesitant to begin drug treatment for my osteoporosis

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@gently

artiste181, welcome, this is a really good site.
I suggest that you try Tymlos and follow windshores as your guide. You can access all of her posts by clicking on a @windyshores.
My short opinionated rundown follows:
There are very few pharmaceutical options divided into drugs that build bone and drugs that preserve old bone.
The anabolics are Tymlos and Forteo, eliminating Forteo because you had side effects.
All of the bisphosphonates work by preserving older bone. I don't like the mechanism of action, so I don't even bother with the side effects. Except with Prolia, which I think the most dangerous of all of the meds, also the easiest to take. Bisphosphonates preserve older bone by preventing remodeling. Prolia has a different mechanism of action. It prevents the bone destroying cells from fully developing collecting what has been called a resevoir or a pool of those cells which mature when you stop the medication. So you have to follow Prolia immediately with medication to prevent extreme damage to your bones.
Then there is Evenity the newest medication (with a scary a black box warning for stroke and heart attack) begins as an anabolic and ends as an antiresorptive.
So I'm for Tymlos. It has an advantage in that if you have side effects you can reduce the dose with the windyshores method or stop taking the drug. It leaves your system withing 24 hours so you aren't trapped with a month of side effects.
Everyone will have a different opinion. I wish you luck with a tough decision.

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Replies to "artiste181, welcome, this is a really good site. I suggest that you try Tymlos and follow..."

@gently
What are your thoughts on forteo? I have done reclast for the past 3 yrs. I previously had a fracture at t8 in 2022. Just went through breast cancer and had 20 radiation treatments apr 2024. I fractured again apr 18 2025 t9 and t10. My spine had improved greatly with reclast. -1.3 .
Think radiation affected it. Now endo wants me to start forteo. I have reclast infusion june 24th. Fearful to start forteo because I have heard it can cause bone cancer. I know it will only be 24 months on it.Then back to reclast. My bone density test is june 9