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Side effects of exemestane (Aromasin)

Breast Cancer | Last Active: May 18 5:56am | Replies (23)

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@dlmdinia

I've been on all three, Exemestane, Anastrozole and Letrozole. I was only on Exemestane for 30 days as my insurance didn't cover it. From comments I've seen on Connect it seems as if Exemestane possibly has the worst side effects. But everyone is different, so who knows how anyone would react. My suggestion would be to discuss with your oncologist switching to one of the other AI's. My knees got horrible after a year on AI's so I started taking collagen supplements (I prefer the capsules). They are back to normal, but I still have back and torso pain. I now wonder if that is (partially?) the Prolia I'm also on. Fingers crossed you find relief somewhere.

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Replies to "I've been on all three, Exemestane, Anastrozole and Letrozole. I was only on Exemestane for 30..."

I started on letrozole for three months, the first month I was fine then I felt horrible so we went off of it. I did not take anything for two months and he started me on exesemtane and the same thing happened, felt fine for the first month and then felt worse, terrible body aches and pains, my joints hurt and my hands are horrible. Ended up at a hand surgeon that said I have now carpal tunnel. They believe it is from the drug. So I have now gone off of the exesemtane I’ve been off of it for two weeks. I feel so much better. I do not think I’m gonna take any of these medication’s. My oncologist radiologist who did not write the script said very few people can take these drugs and she felt everything I have been through radiation and chemo and surgery that I should Be good. She also said at the end of the day it’s your quality of life. I had stage one breast cancer two cells. One was stage one , and the other one was actually a stage zero. I have heard from a couple people that they take the five year pill every other day and one girl takes it three times a week and they feel much much better. I may give that a shot in another month. My main objective now is to try to get my hands to feel better. If I start the pill again, I will do it every other day and see how I feel if things are the same I’m gonna stop altogether. It’s not worth it to me to feel horrible every day, and I do know Side effects are really bad. All doctors have told me that, including the heart doctor.