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Gently, thanks for your reply.
Yes, I will be using bone markers. I've read both McCormick books and met with him where we discussed them. I'm not aware that he does not recommend risidronate. In my case, I've used alendronate in the past without issue. He suggested alendronate after Forteo. Fortunately my endo agreed to baseline CTX, P1NP, and Dexa prior to starting Forteo. She also agreed to three and eighteen month CTX/P1NP tests.
I'm currently 66 and concerned that I will run out of runway on osteoporosis meds (because I plan to live to 100... smile. I'm very active). My endo gave me the choice of Forteo, Tymlos or Evenity. I selected Forteo for various reasons but also for it's 4 yr lifetime use. I'm really curious to understand sequencing of these drugs. Any sources you or others could provide would be great.
Replies to "Gently, thanks for your reply. Yes, I will be using bone markers. I've read both McCormick..."
Same age, same boat🤗
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I like Dr. Ben Leder's YouTube video Combinations and Sequencing of Approaches to Osteoporosis.
Bone markers showed that Tymlos was getting tired at 18 months, but I continued for the full two years. I would not continue for more than that. @gently's ideas on keeping bones receptive to more anabolic use by using a milder anti-resorptive are interesting.
As I wrote before, if initial treatment gets us to a place we are happy with, I think a full Reclast treatment, for however many infusions (could be one) are needed, makes sense Reclast, it is said, lasts 10 years in the system.
All the studies I have seen about an anabolic after a bisphosphonate involve alendronate. I am unable to take orals though.
The whole issue of long term treatment seems understudied and we are, in a way, guinea pigs!