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Letrozole and TMJ?

Breast Cancer | Last Active: May 13 8:34am | Replies (17)

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@maryh62

Hi Bloncape,
I am experiencing the same reaction from my Mayo oncologist. He said TMJ is not a SE. I took 2 AIs and Tamoxifen over the last 10 months. Both of the first 2 times I stopped, the headaches went away. I suspect they will now too as I'm stopping the drug. It's very disappointing.

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Replies to "Hi Bloncape, I am experiencing the same reaction from my Mayo oncologist. He said TMJ is..."

Hi Maryh,
I’m sorry to hear that you experienced headaches and TMJ. Joint pain is a well known side effect of aromatase inhibitors. Since the jaw is a hinge-type joint, why do oncologists deny that TMJ can be caused by taking an AI? If it goes away after stopping one of these drugs, it seems to me that there is a causal relationship. BTW, I also had daily headaches which also subsided after stopping anastrozole. The decision to stop taking these drugs is stressful and not easy to make, but quality of life matters. For some of us, the physical price we pay is too high.
It’s most discouraging, that tamoxifen and aromatase inhibitors have been prescribed for 50 and 25 years, respectively. In all those years, drug companies have not been able to develop effective breast cancer treatments with fewer and often life-changing side effects.
I wish you a good quality of life for many years to come.