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What's your experience with Orgovyx (relugolix)?

Prostate Cancer | Last Active: Nov 8 3:43pm | Replies (171)

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@ava11

I started Orgovyx on April 1st and my last SBRT treatment(fifth) was on April 18th. My RO asked me to come back after 3 months with my PSA and Testosterone results. It so happened that I had a blood draw on April 30th for a blood test ordered through Function Health and I just got the results today.
My total PSA: 2.1 ng/mL
PSA Free: 0.9 ng/mL (43%)
Testosterone total: 8 ng/dL
My PSA was 13.0 before the treatment. Orgovyx website says, PSA drops by 83% in 29 days for most people. That is exactly what happened in my case!
My testosterone before treatment was around 325. It is low but may be ok for my age!
I am surprised how much it dropped!

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Replies to "I started Orgovyx on April 1st and my last SBRT treatment(fifth) was on April 18th. My..."

Thank you for that helpful post. I started Orgovyx on April 22 and I have bloodwork scheduled for May 21. I’m just shy of 69 years old and my testosterone was 266. I expect that number to be below 50 by my blood draw. My last PSA after RT was 0.44 so I’m hoping that that will be down to 0.07 before I start RT. Good luck on your journey.

10+ yrs post rp
Psa rise at 7 yrs
Psma showed 3 pelvic nodes psa 3.6
Treated with 5 SBRT
Psa .6 began to rise 2 years later
Psma showed previous nodes resolved
But one new perimeter node. Psa .85
Started Orgovyx 7 weeks ago
Psa .1 testosterone. Down fron 435 to 6
Some fatigue at first and blood sugar issues and achy back.
Added xtandi
All through ucla