Hi, I was diagnosed with NTM. I've been told to take 3 antibiotics everyday for 18 months. This is how I do it. I set my alarm for 6:30am and as soon as it goes, I take the 3 antibiotics. I take a good measure of water with each tablet. Then wait 30 minutes, I eat a slice of toast and a banana, then I take 1 pyridoxine vitamin tablet. When that's all done I have a prebiotic drink. I can honestly say hand on heart I have not once felt ill or had to run to the bathroom. Getting it all by with in the morning was the best thing for me. I've got all day for my body to recover. Hope that helps. All the best Julie.