My husband has taken D-mannose for several years because of frequent bladder infections. He has the beginning of a UTI less than once a year now and can get rid of that by increasing the D-mannose for a few days. He sprinkles 1/2 tsp on his cereal but his jar of powder says to take with water or your favorite beverage. Do not put it in an acid liquid as acidity destroys what it does. His jar also directs a scoop (2.5 grams) 3 times a day and untill you break the cycle of infections that is probably a good idea. My husband 's dosage would be considered a "maintenance" dose. When he feels a possible UTI coming on he takes 2 D-mannose capsules (700mg/cap) 2x/day for several days or he could just increase the powder. The capsules are nice for traveling. We found out about D-mannose on our own (I am an RN) and it is good that you have started it. May I ask how you learned about it? Wish more MD's would tell patients about it. My husband also takes cranberry capsules since he doesn't care to drink cranberry juice. We order our supplements from Swanson and I should google D-mannose for some cost comparisons. I am just now seeing you first posts as I have not been keeping up with Mayo Connect the past few weeks. I cannot say enough good things about Mayo Connect!!!