When I first get up in the morning, I take two pills of Rifampin with a glass of water, then wait an hour to eat my breakfast. At night with my dinner I take the Ethanbutol and azithromycin with my dinner. During the day I take a probiotic, Jarro Dophilus, 1 tab twice a day. I don’t have any tummy problems doing it this way. I have to take the meds every day. Over ten years ago, I took the same meds three times a week for about a year, but MAC came back recently. I wasn’t good at nebulizing the first time I had it. Now I nebulize 2xD.