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Starting MAC treatment with "big three" drugs: What to expect?

MAC & Bronchiectasis | Last Active: May 8 5:56pm | Replies (192)
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@mokie

Hello, MaryJo

I am on rifabutin, clofazimine, amikacin and ethambutol, so it's part of the Big 3.
I have noticed extreme fatigue from this regimen, but I think it's mostly the ethambutol. I don't think you're imagining it. The medication is strong, and no doubt can cause fatigue--at least that's what I noticed is listed as side effects for some of these. Are some days worse than others? That's what I noticed. Please drink a lot of water to flush the toxins out and help save your liver and kidney functions. That might also help with the fatigue.

Mokie

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Replies to "Hello, MaryJo I am on rifabutin, clofazimine, amikacin and ethambutol, so it's part of the Big..."
maryjo143 | @maryjo143 | May 8 5:05pm

Mokie, Thank you! I will force water, I am a terrible water drinker. I prefer my water hot, filtered over coffee grounds. Bad, I know, but I do not put any sugar or cream in it. I tried to remember back when I started getting more frequent infections and I thought taking antibiotics always made me tired. Taking the big three is a massive amount so it figures I would be fatigued. 😊😊😊

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