I had been taking Wellbutrin for 10-15 years when I felt like I was sliding back toward the dark hole of suicidal depression from which I spent 8 years climbing out. My psychiatrist prescribed Mirtazapine 45mg as an add on, and it's been a good maintenance combination. I never noticed any negative side effects and haven't ever tried stopping it. I don't want to mess with what's working to treat my major depression.

Because of my history of suicidal ideation my doctors are attentive to my mental well-being, which I surely appreciate. Managing medications for multiple medical conditions requires an ongoing need to be especially aware of interactions between my meds. Sometimes I have to weigh the benefits with the risks, and watch out for any problems. I've certainly had an education! There are times when being obsessive about being informed pays off.

I'm wondering what side effects others have experienced. I don't take Mirtazapine for sleep - I use a BiPap because of sleep apnea.

Jim