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Reclast after Forteo?

Osteoporosis & Bone Health | Last Active: May 28 12:34pm | Replies (42)
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@janflute

I do not know if Dr. Mannstadt checks bone turnover markers. I see him on May.15. By a gentler antiresorptive, could that be Fosamax? I took Fosamax from 2003-2008 and had no side effects, but I do not think know if it helped very much..

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Replies to "I do not know if Dr. Mannstadt checks bone turnover markers. I see him on May.15...."
mayblin | @mayblin | May 3 7:30am

@janflute All bisphosphonates have similar physiochemical properties, but their antiresorptive activities differ substantially. For example Reclast is stronger than fosamax, and fosamax is stronger than boniva or actonel. Then there are differences in the “stickiness” to bones among the bisphosphonates. Fosamax can stay in bone for up to 10 years. The length of the “stickiness” also depends on the rate of bone turnover. By comparison, the terminal life of risedronate/actonel is only 20 days.

Ask your endo to choose a sensible bisphosphonate for you, depending on your goals and strategy going forward, short and long term. I think the “gentleness” as well as the terminal life of each bisphosphonate will make a big difference, if you are going to have a second round of FORTEO.

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