I used to be on a different drug. I think it was anastrozole but I did experience joint pains. My doctor told me to start taking glucosame/chondroitin (which also has turmeric & MSM) which I did and the pains disappeared. However, at the same time she changed me to exemestane. But I'm continuing the glucosame/chondroitin because it can't hurt. Exemestane is supposed to suppress estrogen and put one into menopause (either your first or second). So the symptoms of menopause do include heart palpations. But now they want me to go get my heart checked.