@barbb22, There are some member comments on MSM (Methylsulfonylmethane) in a few other discussions on Connect that you may find helpful. Here is the search link that lists the discussions and comments - https://connect.mayoclinic.org/search/discussions/?search=MSM.

Here's an article on MSM if you haven't already seen it:
--- 8 Science-Backed Benefits of MSM Supplements:
https://www.healthline.com/nutrition/msm-supplements