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Replies to "My P1NP was 54 pre-treatment. After 16-18 months Tymlos it was 40, then 35. After one..."
Osteoporosis & Bone Health | Last Active: May 1 8:26am | Replies (20)
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My P1NP was 54 pre-treatment. After 16-18 months Tymlos it was 40, then 35. After one month Evenity, 33, and in the middle of the 3rdmonth 39. Very disappointing for Evenity. For the Tymlos numbers, the testing may have missed the high point at a year or so.
DEXA's spine 6/21 -3.7 4/23 -2.5 (20% gain after 18 months Tymlos)
hip -3.3 -2.9 (9% gain)
femur neck -4.1 -3.6 (the reason I did some Evenity)
Replies to "My P1NP was 54 pre-treatment. After 16-18 months Tymlos it was 40, then 35. After one..."
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@windyshores, Your baseline CTX may not be accurate due to blood collecting time and morning food. According to what is known about circadian and food effects on CTX, your baseline CTX might have been higher than 324. Also it didn’t appear that you had btms tested during anabolic phase of tymlos so the btms at 16-18mo of tymlos might be at the tail end of therapy. These might explain your earlier btm results? Wish you had btms tested at 3, or6 or 12 mo of tymlos. Despite all this, you had such a wonderful Dexa results, a true success story of tymlos! Then your btms readings during evenity is most perplexing. No pattern for CTX, or P1NP. Please keep us posted of your next Dexa if you could. It will be interesting to see how it comes out.