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bone markers

Osteoporosis & Bone Health | Last Active: May 1 8:26am | Replies (20)

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@dna41

I would like to know what is considered low CTX. Mine is 300. Is that low?

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Replies to "I would like to know what is considered low CTX. Mine is 300. Is that low?"

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@dna41 is this your baseline CTX? Do you happen to have P1NP tested at the same time also?

dna41,
normal stretches from 104 to 1008. Your number though (if you are still on Prolia) drops after the shot (by as much as 80% initially) and gradually rises until your next injection.
You may know that Prolia works by repressing the cells that break down the bone. CTX is a measurement of that process. P1NP reflects bone that is building. It will also be lowered by Prolia injections. Prolia doesn't build bone but collects old bone thereby increasing BMD. The repressed cells that breakdown bone collect as a resevoir of precurser cells that are released when you are late for or stop taking the injections.
That is why it is so dangerous to stop the drug without following with a drug that will give you protection from those resevoir cells.
Do you have a baseline CTX. Do you have P1NP numbers? How far inbetween injctions are you. Were you able to find a provider with a license to prescribe Prolia?