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Does Kevzara put PMR in to remission?

Polymyalgia Rheumatica (PMR) | Last Active: Aug 14 5:50pm | Replies (18)

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@dadcue

"Conclusions: Sarilumab showed significant efficacy in achieving sustained remission and reducing the cumulative glucocorticoid dose in patients with a relapse of polymyalgia rheumatica during glucocorticoid tapering. (Funded by Sanofi and Regeneron Pharmaceuticals; SAPHIRE ClinicalTrials.gov number, NCT03600818.)
https://pubmed.ncbi.nlm.nih.gov/37792612/
Remission isn't achieved in all cases but a sustained remission was achieved in significantly more cases than with prednisone alone. People are sometimes able to discontinue Prednisone but many need to stay on Kevzara. Other people achieved remission and can also discontinue Kevzara. There may be significant side effects from Kevzara so there are pros and cons to Kevzara and it can be expensive.

I don't have any personal experience with Kevzara. However, Kevzara is FDA approved for the treatment of PMR. In most cases it is used for relapsing cases of PMR or for people who don't tolerate prednisone well --- I would guess that might include almost everyone.

If you have osteoporosis then prednisone might not be the best medication for you.

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Replies to ""Conclusions: Sarilumab showed significant efficacy in achieving sustained remission and reducing the cumulative glucocorticoid dose in..."

Thanks for replying to my question!

You are so right about me getting off steroids. I have done some research about Kevzara, but need to do more, especially about the side effects. Thanks again. This is an awful disease with no real end in sight.