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Prolia adverse events over 10 years - ONJ, AFF
Osteoporosis & Bone Health | Last Active: Apr 30 4:14pm | Replies (18)Comment receiving replies
10 years on Prolia, stopped Prolia, Reclast, 2 weeks in the bed, thought wouldn't go through, after4, 6, 8 months of infusion high CTX, insurance refused give me Reclast even for my money, and no low dose at all, endocrinologist prescribed alendronate, that's all and I had fracture of my hand 5 months ago.
From my experience Prolia did not help me much, will come to the begining of treatment. My advice for new patients, look more and more what to do.
Replies to "10 years on Prolia, stopped Prolia, Reclast, 2 weeks in the bed, thought wouldn't go through,..."
Sorry @whitesman , I have a bunch of questions but will settle on this one. Did you have any fractures during the 10 years of Prolia?
BTW, the CTX overshoot should only last about 18 months or so. Hopefully you can make it through without losing too much BMD. Alendronate is a good drug do don't be too put off about not taking Reclast. If you wait 2 hours after taking alendronate instead of 30 minutes before eating (use low calcium water if you can), you can get up to 40% better absorption. This is called out in the package insert if you want to look it up. Calcium stops alendronate in it's tracks.
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Sorry to hear about your experience. It sounds like you did everything by the book and yet still had runaway CTX. That's what I'm afraid of since I have a high baseline CTX. I guess I will find out in about 10 years or so. I plan on trying alendronate right after Prolia then switch to Reclast when my CTX goes above my baseline. No trials to prove it out yet, but it might work.