← Return to Bone turnover markers (CTX and P1NP): do you have a baseline?

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@mayblin

Hi @michaellavacot your choice of prolia after evenity was sure an interesting one at a time when most ppl think twice before starting it. I’m sure you are familiar with the mechanism of action of prolia as well as the mechanism of its rebound effect upon cessation.

In your special case, the hupercalciuria sounds the underlying cause of your op, the use of antiresorptive seems making most sense than an anabolic at the moment. I wonder if your blood calcium level, especially vital organs which need calcium to function get affected with an antiresorptive. Treatment and management of hypercalciuria definitely is a key here.

Hope you will use btms especially CTX to guide your therapy, especially during withdrawal of prolia when that time comes!

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Replies to "Hi @michaellavacot your choice of prolia after evenity was sure an interesting one at a time..."

Hi @mayblin - I have done a lot of research on Prolia, a lot. I even put together a training on Prolia that I have presented to a BHOF support group. The recording of the session is here https://youtu.be/XiRN3UvOEYg?si=Cvi4LnK9uEejykPr .

Yeah, I'm convinced my hypercalciuria is my problem. You can't build bone if you are peeping out more calcium than your intestines can absorb. I'm working really hard on that problem. I'm even combing through my genome to find the issue. I have an upcoming appointment with the best nephrologist I could find next month.

Thanks for your support. I appreciate it. 🙂