Prolia causes a rebound effect when you stop it. Your bones go back to worse than baseline and fracture risk is increased. So you must stay on it forever (which, depending on your age, might be a reasonable course of action as long as you're not having any side effects that you can't live with) or take a bisphosphonate after going off Prolia. Whatever bone drug you take, whether antiresorptive or anabolic, is going to have side effects which you personally may or may not experience. If you decide to do Prolia, know what the side effects are and if the benefits for you outweigh the risks to you. Different people will answer that question differently. The main problem with Prolia is the rebound effect which is unique to that drug. If you find you can't tolerate it for some reason, you can't just stop it. You must take a relay bisphosphonate. Those have their own side effects to consider. You'll also have to consider what your insurance will cover. It's worth a discussion with your doctor for what the exit plan is for coming off Prolia.