1. < Prostate Cancer

Can anyone share their experience with Nubeqa?

Posted by markagottlieb @markagottlieb, Apr 23 12:05pm

my husband will start Ubeqa this week. I would like to know others experiences.

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stevecando54 | @stevecando54 | Apr 23 4:43pm

maybe Colleen can help with this but you might of spelled the treatment wrong. best to you

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lag | @lag | Apr 24 7:43am

It is Nubeqa. The misspelling is probably why you haven't gotten responses yet.

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round5 | @round5 | Apr 24 8:13am

I’ve been on it for over 10 months but since it is part of my triplet therapy can’t really rate it. I still rate Leuprolide as the evilest of the drugs.

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wooldridgec | @wooldridgec | Apr 25 7:59am

I was diagnosed with De nova metastatic prostate cancer June 2022. After Radiation treatments to my spin and ribs and 30 days on Casodex, I started qurterly Eligard injections and montly Zometa infusions. Along with Eligard and Zometa, I was started on Chemotheropy and Nubeqa (Darolutamide). So, I've been on Nubeqa (Darolutamide) almost 2 years. It is a miracle drug. I highly recommend that you do triplet therapy and take Nubeqa. All studies show that Nubeqa works better than all the other ARI drugs such as Enzalutamide or Apalutimide. The others are great but none has tested better than Nubeqa for Overall Survival and time to Castrate Resistance. To date, time to Castrate Resistance when taking an ADT, Nubeqa, and Docetaxel (chemotherapy) has not been reached. It has been over 5 years since the ARSENS trial ended. Nubeqa also does not break the brain blood barrier so you will not have continued fogginess or forgetfulness. I am a high end Software Developer/Architect and it does not affect me cognitively at all. The ADT (Eligard) and Nubeqa do give me terrible hot flashes. But, that is a trade-off I am willing to accept. If you are chemo healthy and you feel you can handle more than 6 chemo treatments, I recommend you do so. I did 10 treatments. But everyone is different and can handle what they can handle. The increased chemo treatments also increases Overall Survival (OS). The more micro metastases you kill up front, the better chance you kill any cancer cells with other mutations. The only treatments the doctors offer to kill the cancer is radiation and chemo. ADT and Nubeqa stop the creation of testosterone which the cancer feeds off. So, in my mind I wanted to Carpet Bomb the cancer with radiation and 10 chemo's. Had my doctor agreed, I would have done 12 cycles. But, I was able to handle it, because the Lord Almighty made it so I could. For that, I am thankful. Lastly, I will say the more chemo treatment the longer the recovery. I am just now starting to feel more energy. I do not need a nap in the afternoon anymore. My PSA is undetectable and my latest bone scan showed no evidence of cancer (rather stable metastatic disease). God Bless You. Be healed in the name of Jesus.

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1 reply
markagottlieb | @markagottlieb | Apr 25 5:44pm
In reply to @wooldridgec "I was diagnosed with De nova metastatic prostate cancer June 2022. After Radiation treatments to my..." + (show)
@wooldridgec

I was diagnosed with De nova metastatic prostate cancer June 2022. After Radiation treatments to my spin and ribs and 30 days on Casodex, I started qurterly Eligard injections and montly Zometa infusions. Along with Eligard and Zometa, I was started on Chemotheropy and Nubeqa (Darolutamide). So, I've been on Nubeqa (Darolutamide) almost 2 years. It is a miracle drug. I highly recommend that you do triplet therapy and take Nubeqa. All studies show that Nubeqa works better than all the other ARI drugs such as Enzalutamide or Apalutimide. The others are great but none has tested better than Nubeqa for Overall Survival and time to Castrate Resistance. To date, time to Castrate Resistance when taking an ADT, Nubeqa, and Docetaxel (chemotherapy) has not been reached. It has been over 5 years since the ARSENS trial ended. Nubeqa also does not break the brain blood barrier so you will not have continued fogginess or forgetfulness. I am a high end Software Developer/Architect and it does not affect me cognitively at all. The ADT (Eligard) and Nubeqa do give me terrible hot flashes. But, that is a trade-off I am willing to accept. If you are chemo healthy and you feel you can handle more than 6 chemo treatments, I recommend you do so. I did 10 treatments. But everyone is different and can handle what they can handle. The increased chemo treatments also increases Overall Survival (OS). The more micro metastases you kill up front, the better chance you kill any cancer cells with other mutations. The only treatments the doctors offer to kill the cancer is radiation and chemo. ADT and Nubeqa stop the creation of testosterone which the cancer feeds off. So, in my mind I wanted to Carpet Bomb the cancer with radiation and 10 chemo's. Had my doctor agreed, I would have done 12 cycles. But, I was able to handle it, because the Lord Almighty made it so I could. For that, I am thankful. Lastly, I will say the more chemo treatment the longer the recovery. I am just now starting to feel more energy. I do not need a nap in the afternoon anymore. My PSA is undetectable and my latest bone scan showed no evidence of cancer (rather stable metastatic disease). God Bless You. Be healed in the name of Jesus.

Jump to this post

Thank you so much for your answer! My husband starts Nubeqa tomorrow. May I ask your age when diagnosed?

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wooldridgec | @wooldridgec | Apr 25 9:10pm

I was actually diagnosed July 27, 2022, my birthday. I am 61 years old now. How old is your husband?

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wooldridgec | @wooldridgec | Apr 25 9:12pm

What was your husbands PSA at diagnosis and what is it now? Is he responding to Eligard?

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Moderator
Colleen Young, Connect Director | @colleenyoung | May 1 9:12pm
In reply to @markagottlieb "Correct spelling is Nubeqa" + (show)
@markagottlieb

Correct spelling is Nubeqa

Jump to this post

Jumping in late, apologies.

@markagottlieb, I corrected the spelling in the title too. In addition to the responses you got from members already, you might also want to check out these 2 related discussions:
- Nubeqa and Lupron
https://connect.mayoclinic.org/discussion/nubeqa-and-lupron/

- Have you used Nubeqa or Zytiga?
https://connect.mayoclinic.org/discussion/have-you-used-nubeqa-or-zytiga/

Will your husband be taking Nubeqa alone or in combination with another drug? How is it going so far?

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