Thank you so very much for your reply and your time. I had been wondering if there was a treatment or a medication that I was overlooking . I guess there is not. I feel bad for you at night time, night time is the worst time when we can’t get sleep. I totally understand the torture of shoes and socks. Dr. Jay Cohen Sounds familiar, I will look him back up. And I will look into the Erythromelalgia association And find other members with EM. Thank you for telling me that you have contacted others and you have found no help also. I did come across this week a med. called pentoxiphylline. It helps a few people by helping with the viscosity of the red blood cells that could possibly get congested in the small arteries that get dilated because of the dysfunction of nerves and blood vessels. It also states it has many anti-inflammatory effects. My pharmacy had to order it so I have not started on it yet. I asked my primary doctor if I could try it after I read about it and she will start out with a very low-dose to see if I have any bad reaction to it. in another article, it states that it really does not do much. I had bad reactions to so many of the medication for the pain. My leg swelled up When I tried gabapentin. If the medicines did not give me a bad reaction, and I was able to take it, they did not help at all. The pentoxifylline Helps the blood flow by making the blood cells more slippery. I pray you are able to find some relief, and that you can get things done on your overgrowing list of things to do. God bless you.