Many people experience nausea as a result of excess acid in the stomach. This occurs more when stomach is empty, particularly in the middle of night. It’s also seasonal, worse in spring and fall. The excess acid is likely to cause ulcers, and sometimes nausea is the main symptom without pain. Gallbladder disease causes nausea when stomach is full, after eating, especially after fatty food intake. The nausea from excess acid is temporarily relieved by creamy foods like ice cream, yogurt or milk, made worse by alcohol and spicy or acidic foods. Observing these associations can provide clues as to the cause. A test of antacids is helpful. If antacids relieve the nausea, then an H2 blocker like Pepcid (famotidine) and /or a PPI (protein pump inhibitor like omeprazole ) both OTC, can help if taken daily. Of course a discussion with your doctor about your observations and response to these meds is appropriate and so is asking for an endoscopy and gallbladder ultrasound. I hope you get some answers soon and relief!