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PMR and MGUS/SSM/MM multiple myeloma

Polymyalgia Rheumatica (PMR) | Last Active: Dec 12, 2024 | Replies (19)

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@menetski4

In summer of 2023 I was dealing with a lot of upper back pain. Finally I was diagnosed with MGUS (+M spike, but normal light chain ratio). On MRI I was found to have a compression fracture of thoracic 6th vertebrae - cause unknown, I have osteopenia but not osteoporosis on DEXA. It has taken 10 months to heal the vertebral fracture, but now I fear I may have another in my lower spine, partially due to a recent incident where I was assisting an individual who had fallen and I felt sharp pain in my back. It is now presenting just the same way the thoracic fracture had in the past.
Back in January 2024 I awoke and couldn't walk across a room with pain primarily in my pelvis. It was diagnosed as PMR and responded to Prednisone 20 mg. I am tapering off the Prednisone and now at 12.5mg but it is complicated by the recent incident with my lower back. I will see a rheumatologist and an oncologist in early June to evaluate condition, along with new labs. Meanwhile I do my best to address nutrition (whole food, anti-inflammatory diet), stress (meditative and mind-body pain practice), exercise (walking 2-3 mi/day, moderate weight training), relationships (faith, family, love, and public health education on brain health), sleep (9p-5a). Sleep has been an issue with the back pain and PMR. I wake up in the middle of the night with pain and I am stiff and sore in the morning until I move around for about an hour.
Hope that helps! Best to you...

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Replies to "In summer of 2023 I was dealing with a lot of upper back pain. Finally I..."

I simply wanted to post here because you are the first person I have come across that has had compression fractures and has also been diagnosed with MGUS. I also was slightly above osteopenia level on DEXA, not quite there yet, so I began my quest to find out why the compression fractures keep happening to me, none of my 3 (or more) were due to any trauma, just ordinary activity. Super painful, and they can take a long time to heal. Very much interferes in daily life, especially for the first 2 weeks or so, and since learning that that was what happened the first time, I have known the following two times that was what had occurred.

This is the first I have heard of PMR, so far no Dr has thought this a possibility. Interesting. I do have many of the symptoms, but this still does not indicate why my spine continues to fracture or compress. I had no treatment other than some chiropractic treatment during some of the times of fractures - and I wouldn't really recommend that.

Sometimes it is helpful just to know you are not alone, thanks for sharing your journey.