Small PSA Rise: What might be the cause?
I completed proton beam therapy October 30th 2023 for one core Gleason score 3+6 and I took my third PSA test last week having a small rise.
My original PSA was originally 4.8 prior to the biopsy and the proton beam therapy)and went down to 3.5 and then 2.2 and yesterday's results were 2.66. I had a hamstring injury over the last four weeks - still healing and I'm wondering if that could've affected the PSA because the groin did have some pressure. I am seeing my doctor this Friday. I welcome your comments.
Alan Russell
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Yes, a doctor told me that mildly-elevated PSA just shows that there's some kind of stress on the prostate (assuming it hasn't been removed or radiated), not necessarily cancer.
Once the prostate has been neutralised (either by removal or radiation), however, then there's a stronger correlation between PSA and cancer progression, because the PSA is likely coming from prostate-cancer cells elsewhere in your body.
so it looks like a hamstring injury can't put pressure on the groin very similar to when you ride a bicycle that's pressing against the prostate from the seat that can cause a rising PSA. thanks for getting back
meant "can"
Likely just a bounce. People who have bounces tend to have better long-term outlooks!
Do you have a link that states that positive outlook.
https://www.mdpi.com/2072-6694/12/8/2180/review_report
thank you for the link - very interesting study.
Alan
@saxman911
It appears you are doing good. Your R/O should have discussed minor rises in PSA with you. It is very common to have slight rise in PSA numbers over the years after treatments. If you have had RP then a rise in PSA numbers would be much more of a concern.
Infection, bike riding, vigorous sex, etc. can cause a rise in PSA numbers. Your R/O should have explained this. What my R/O and PCP told me was if the PSA continues to rise that is when there is a concern not a single jump here and there.
I am not a medical professional just passing on what my R/O told me as well as my PCP.
thanks so much for the reply and of course I will discuss this with my urologist this Friday.
Get PSMA scan