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My husband has stage 4 metastatic prostate cancer
Prostate Cancer | Last Active: May 2 9:52pm | Replies (40)Comment receiving replies
The WHO-standard for an "ultra-sensitive" PSA test (often used for high-risk patients, like those of us with stage 4 PC) is 10× as sensitive, going all the way down to 0.01 ng/mL. When your result is still "undetectable" using that test, you're in pretty good shape. I'm grateful that Firmagon (Degarelix) + Erleada (Apalutamide) have been keeping me there since 2021.
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That seems a bit of a grey area at this point. Dr. Scholz suggested driving PSA further and further down from 0.1 does not seem to provide better outcomes. May be more data in a few years time will provide some clarity?
Agreed on reading too much into studies. The better ones do give warning that result is based on data collected some time back. It may no longer be valid.
Also most of these studies are written for professionals. It is better to read them with qualified medicals. For example, the small print of one of these studies said that the cut off is PSA = 0.5. Well, we know that there is a great deal of difference between 0.5 and 0.1. These studies were conducted purely to demonstrate that one drug or one treatment is better than others.
So much for the layman's rambling.