Beanieone, hi.
People are taking Evenity with good results. If there were no other (partially anabolic) drug, I'd be taking it. Some people are taking Evenity without gain and some with adverse effect.
There is a black box warning on Evenity with regard to cardiovascular events-stroke, mI, and athersclerosis.
The mechansim of action of Evenity is the blocking of a sclerostin pathway. Sclerostin has long been though to be preventive against the accumulation of placque in our arteries most especially in the heart valves.
This mechanism may prove to be safe or safe in a years long use of Evenity. We'll know because of the brave souls investigating the medication in their own bodies.
Heart disease is the #1 cause of death in the US, #2 in Canada.
Osteoporosis has no "end stage."
Forteo has been around for decades ( I write decades because I can't remember the year). It has a high safety profile. Adverse events can be as brief as several hours because you can quit the drug overnight. You are really trapped for at least two month if you have adversity with Evenity's application.
In general, I prefer a osteoporosis medication that builds bone. Evenity does that for the first few months and then becomes anti-resorptive. I don't want osteoclast reduction because I want bone turnover to make my bones stronger.
I would cheer anyone taking Evenity, but would't encourage anyone to take it.
I've just finished by 12th Forteo pen, and quite like the medication, though I know it isn't good for everyone.