Hello @janetsimmons

I too have hypercalciuria and there's a real good chance your T-scores are where they are because of your hypercalciuria. It's impossible to build bone if you are peeing out more calcium than you can absorb. The body cannot make calcium.

Based on my research, assuming you can make a significant change in reducing your urine calcium, you could very well see an increase in your bone density. While I don't think it will be enough to get you out of the osteoporosis range, I think your risk of fracture is likely not too high so you could try your diuretic for a year and get a new DXA scan.

That said, while your waiting, try to eliminate all other secondary causes of osteoporosis to give yourself the best chance. You will want to get some bloodwork done to check for secondary causes (like vitamin D levels) and ensure you are getting enough calcium in your diet. I recommend a bit over the recommended 1200mg if your urine calcium is still high while on the diuretic.

Personally, I was at -3.7 with a urine calcium of 550mg/day. While I was able to reduce that number to about 370mg, I had a poor response to my Evenity treatment. Again, you can't build bone if you are peeing out a significant portion of what you can absorb.

Side note: I have tried various doses of hydrochlorothiazide, chlorthalidone and now indapamide. Depending on your dosages, you might have to supplement with potassium. I started having irregular heart beats due to not taking my potassium.

I wish you the best of luck!