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Prognosis for Stage 4 Metastatic Prostate Cancer

Prostate Cancer | Last Active: Apr 17 10:20am | Replies (95)

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@northoftheborder

I think chemo with the up-front "triple treatment" for stage 4 is used only if there are lots of metastases and/or the cancer has become castrate-resistant.

For castrate-sensitive oligometastatic prostate cancer, I don't think chemo would make sense at the start (radiation + ADT + an androgen-reception inhibitor like Apalutamide get the job done), but interested to hear from anyone who's seen otherwise.

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Replies to "I think chemo with the up-front "triple treatment" for stage 4 is used only if there..."

Dr. Scholz put it this way. Chemo represents another path to deal with the cancer cells, by disrupting it's DNA etc. Intuitively, it should enhance the cure rate. So perhaps it will reduce that 10%? Is it worth it? Perhaps that is a matter for the patient and his medical team.
Dont mind me. I am just another layman trying to make some sense of the whole thing.