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Something new in the treatment arsenal?

Breast Cancer | Last Active: May 1 9:04pm | Replies (58)

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@californiazebra

Hi @leeann66
Thank you for the update! Prayers for your scan results! Please update when those come in. It sounds like you're still in good spirits despite some challenging side effects. Yes, neat how they are treating your eyes. New treatments all the time. Also good news that they are submitting Dato-Dxd for FDA approval. Your results to date are encouraging!

Since you're so great about answering questions:

Do they expect you to remain on Dato-Dxd indefinitely or only when there are visual signs of cancer?

Have there been any issues with Dato-Dxd causing peripheral neuropathy as many chemos do?

For perspective, how much does this treatment impact your quality of life compared to the other treatment regimens you've tried (Kisqali/anastrozole, afinitor/exemastane, xeloda)?

Thank you for taking the time to respond. Please keep us posted. Zebra

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Replies to "Hi @leeann66 Thank you for the update! Prayers for your scan results! Please update when those..."

Hello @californiazebra

The plan is that as long as the medication is working, I will stay on it. Fingers crossed that is for a very long time.

In terms of neuropathy, it is minimal.

As for quality of life, as I did with all the other medication‘s, I continue to do everything I want to do, which includes going for walks, dragon, boat practice, spending time with my friends and family and grandkids, travelling, entertaining…

What is different is that some days I do have to take more breaks, particularly in the week following chemo. As well, am regularly through the day having to put a variety of eyedrop’s in my eyes, as well as rinsing my mouth due to pretty significant mucositis. The mucositis also impacts my eating and drinking so that is a bit of a juggling act, but things could be much worse.

That being said, it is all quite manageable just takes a bit of planning and juggling and ensuring I listen to my body to stay as healthy as possible.

With the other medications, Anastrozole and Kisqali gave severe bone pain in particular in my feet and hair thinning, but was manageable.

Affinitor and Exemestane I had a terrible rash and trouble breathing so that had to be stopped pretty quickly.

With the Xeloda, I had nausea every single day, for the whole afternoon, which was more of an issue than what I’m dealing with now.

So long story short, I am living my life and doing all the things I want to do, just with more breaks, more medication’s for side effects and a few more steps to try to be more comfortable, but I’m still doing it all. Hope that answers your questions, feel free to reach out if you have more. Take care, LeeAnn