Timing of the p.m. session is something that I struggle with also. Airway clearance works best when saline neb is preceded by a bronchodilator, such as levalbuterol or albuterol. The latter taken too close to bedtime interferes with sleep. The half life of levalbuterol is 4 hours, which means that after 4 hours 50% of the drug remains, after 8 hours 25% of the drug remains etc. So it can't be taken too close to bedtime.

I wondered about nebbing levalbuterol before dinner and then once dinner digested, nebbing 7% saline, since the bronchodilator will still be somewhat in my system. Anyone try this?