John, thank you for getting back to me. I know there are a lot of people on this site. I find this site very informative. My rheumatologist mentioned methotrexate during my virtual visit on Tuesday. I hadn't researched that drug until then. Sounds like both drugs have pros and cons. I will reach out to her today. My blood tests came back with elevated markers again. She was so on it in the beginning but like this site, I know I'm not her only patient. Thanks, again.