My doctor is recommending Methotrexate. I've done a lot of research on this drug. It says you can't take Prilosec which I take daily. I've had Mohl's surgery and many skin lesions frozen off. It says it can cause cancers. I had breast cancer in 2013. I have an ulcer and a hiatal hernia. All the side effects really scare me. Has anyone tried leflunomide? It's the second choice of treatment but has fewer side effects. I've tapered down to 5mgs, and my pain is back. I just want to wake up one day without pain! Any suggestions would be appreciated.