Hi, there. I have ROS1 as well, but am on Repotrectinib (just started in Feb). Although I'm not having any side effects like what you describe, I DO have a preexisting skin condition with random itchy spots, and I was prescribed Clobetasol Propionate 0.05% and it works like a charm - every time. I suggest maybe you mention this ointment to your derm to see if they might either give you a sample to try, or perhaps they can prescribe it so you can try it for a couple weeks. Best of luck! ♥️