That's a tough call with an aggressive grade 3 cancer, even if it didn't escape the ducts. The main long term side effect of chemo seems to be peripheral neuropathy. No one seems to know the likely risk in individual cases. Some say around 20% of patients. In my case, it's not painful but it makes walking unpleasant. It feels like walking on wet sand. It also increases my falls risk -I'm 76. I no longer drive, though I still have a licence. Tried acupuncture for quite a while but it didn't work. Once those nerves are dead, it seems, they don't regenerate. I don't think enough research has been done on Chemotherapy Induced Peripheral Neuropathy.