I have been off antibiotics for over 4 years and am maintaining with airway clearance, 7% saline, mucus thinners, exercise and Symbicort. I have had only a few exacerbations that required either a short course of antibiotics or steroids. I have pretty good energy and stamina as long as I manage my activity level.
My hearing wasn't affected although my tinnitus became a bit worse. Don't know if it was due to meds because I have had it for over 30 years