← Return to Small Dose Prednisone Therapy

Discussion

Small Dose Prednisone Therapy

Polymyalgia Rheumatica (PMR) | Last Active: Apr 19 10:17am | Replies (14)
Comment receiving replies
@mtr2601

My Rheumy was quite clear in stating that PMR is very debilitating but doesnt do any actual damage to joints and muscles. The damage is done by avoiding movement due to the pain experience. Prednisone takes away the pain by dampening the inflammation but causes a lot of damage and often doesnt 'reboot' the immune system in a sustainable manner.

Jump to this post

Replies to "My Rheumy was quite clear in stating that PMR is very debilitating but doesnt do any..."
DadCue | @dadcue | Apr 8 3:21pm

Can you explain what "reboot" the immune system means? I suspect it has something to do with adrenals being able to produce cortisol. Cortisol is the hormone that is supposed to regulate inflammation instead of prednisone.

"Suppressing inflammation: In short spurts, cortisol can boost your immunity by limiting inflammation. However, if you have consistently high levels of cortisol, your body can get used to having too much cortisol in your blood, which can lead to inflammation and a weakened immune system."
https://my.clevelandclinic.org/health/articles/22187-cortisol

VIEW AND REPLY
glinda47 | @glinda47 | Apr 8 6:35pm

mtr, I'm glad to hear the info from your pmr.....first non terrifying thing I've read!
I was searching the net for the possibility of movement/exercise induced damage to pmr-affected muscles and couldn't find anything definitive.

I hope I don't have to deal with steroids. Just the thought is nauseating.

Thanks for your comment!!

VIEW AND REPLY