Hello! I take Verzenio; it’s a CDK 4/6 inhibitor. “Verzenio is approved for women with HR+, HER2–, node-positive early breast cancer with a high risk of returning, as determined by a doctor, or certain types of HR+, HER2– metastatic breast cancer.” I’m the former, and I take 100mg twice a day to reduce my risk of recurrence. My oncologist is a big fan of this drug. It does cause diarrhea, but it’s easily managed with Imodium, although we did reduce my dose from 150 to 100mg because of nausea/vomiting along with diarrhea. It is obnoxiously expensive (the list price is >$15,000/month 😂), but they offer a “savings card” which magically reduces my out-of-pocket to $0. Since it sounds like you’d take it for MBC, you’d likely be on the drug indefinitely, or as long as it’s tolerated. I believe Ibrance and Kisqali are also CDK 4/6 inhibitors, but I only have experience with Verzenio. I would absolutely encourage you to give it a shot! You can always discontinue it if side effects are intolerable. Take care 🤗