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PMR and Methotrexate

Polymyalgia Rheumatica (PMR) | Last Active: 23 hours ago | Replies (202)

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@jj8431

Thank-you! In addition to my joint symptoms, I had these strange skin lesions, purpura, in, of all places, my groin and my eyelids. I went to a dermatologist, who did skin biopsies, came back Amyloidosis. That sent me on a journey to find an Amyloid specialist, at the Cleveland Clinic, who did a barrage of testing that also found Multiple Myeloma. Both are rare, incurable but treatable, and can mimic PMR and/or RA symptoms. Unfortunately, I had symptoms and un/misdiagnosed for over a year before actual diagnosis, allowing it to worsen. But...I am confident I can, hopefully, achieve a long-term remission. My hope is that other folks and physicians are aware of this as a possibile differential diagnosis.

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Replies to "Thank-you! In addition to my joint symptoms, I had these strange skin lesions, purpura, in, of..."

Wishing you full and successful recovery. I'm trying to figure out how this was diagnosed as PMR. Sounds like you had bone and joint rather than muscle pain. Was your pain bilateral?
Wow. I guess the pred helped so that was all the docs had to hear. Thankfully you took this into your own hands. Very best to you on your journey to excellent health.