I have been taking Prolia since late November 2023. No side effects so far. I did get a blood test done at the one month mark and saw a drop in calcium from about 9.5 to 8.9, so I upped my calcium intake and extra 200mg. Rechecked a month ago and now at 9.3. I also saw a drop in my urine calcium by ~ 100mg/24 hours, which was good and expected. Because I have hypercalciuria, I am ensuring consistent calcium intake to maintain stable blood calcium. Prolia makes it so calcium is not as readily available from the bones. Hypocalcemia has some ready bad effects on the body.