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← Return to Tamoxifen and anastrozole
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Drug companies spend large sums of money for testing to get drugs approved. I have read that they use the highest dose possible with a level of toxicity that will gain approval by the FDA. We only need to listen to ads on TV to understand how many side effects drugs can have and that they are all toxic to some people at differing degrees. Higher doses are more profitable. There is no monetary incentive for drug companies to study the effectiveness of lower doses, so fewer studies are done to determine the efficacy 20mg vs. 10mg, for example. Therefore, nearly all women are given the same high dose, regardless of weight, age (older women metabolize drugs differently), or level of estrogen before taking tamoxifen or AIs which is seldom checked. Some oncologists are beginning to consider lower doses, but that seems to be the exception rather than the rule.
Replies to "Drug companies spend large sums of money for testing to get drugs approved. I have read..."
Hello! And good morning! I am so grateful for this support chat. I had been taking ALL 3 of the AIs and had the COMMON and UNCOMMON side EFFECTS the pelvic pain was first. Then the spotting. Then the cramping of all my joints in my body. The rash aka FUNGUS hands toenails. And private parts. It took 2 years for my dermatologist and I to figure the fungus thing out. By taking meds to CLEAR UP THE FUNGUS. then back on the AIs. I did my research and found out that AIs are a pill form of CHEMO. and because my MEDICAL TEAM has lied to me, in regards to the medicine. I have taken myself off of it.
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I believe that doctors need to take into consideration people's medical history their weight their age and what has worked for 40 years may not be what works now thanks for sharing all that information. Why is it a drug that us suppose to ward off more breast cancer has debilitating side effects its nuts
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Agree… if I hear “ that’s what the research shows us” one more time I might scream.