Ha!, well, I guess I don't have to worry about these side effects anymore. I have been taken off MTX and am being rapidly weaned from Prednisone (1 mg every 2wks, at 6 now then will dc) Why? because I don't have PMR or RA, I had been mis-diagnosed for more than 6 months! I have Multiple Myeloma (cancer of bone marrow plasma cells causing bone destruction, hence the pain) and Systemic Amyloidosis (depositing protien fibers into all my joints and organs)--- a double whammy! I am now on my 5th chemo treatment (1x/wkly, multiple chemo drugs) I will post more (probably in my initial post about PMR) once I have a clearer picture of the type, stage and prognosis, etc. What is important are the symptoms that can mimic PMR and the fact that prednisone masked the symptoms of Myeloma and Amyloidosis.