@06111945cc The Tymos pen as 8 clicks for a full dose. You can feel the clicks. You can start at a full dose and if you have any issues, go back to 2 or 4, whatever you can tolerate. Once your body adjusts, move up. You want to aim for 6 or 7 clicks at least out of 8. Talk to your doctor about this of course. If you refrigerate it, the Tymlos pen can last longer so the reduced dose doesn't mean you have to throw it out at 30 days. I checked this with the company.