I have been on Prolia almost 5 years when I went from osteopenia to osteoporosis. After 2 years my bone density went back yo osteopenia.
So my Endocrinologist has monitored me closely during those 5 years with multiple blood test and is now evaluating me to see if I can discontinue the Prolia. I will have a bone density test first. He did several X-Rays and had me se e a Rheumatologist who did other x-rays and results better than expected. According to recent studies if there’s significant improvement after 5 years one can come off and be given 1 Reclast in 6 months to help prevent rebound. So hopefully I will be one of the lucky ones to succeed in stopping. My Endocrinologist is really into close monitoring and I have been with him for over 10 years.