Thoughts on Prolia?

For others: I cannot handle large doses of medicines that stay in the body, like @artscaping. However I have GERD and cannot take oral alendronate. My doctor is giving me 1 mg Reclast, rather than 5mg, and would even do .5mg, and I can have that every 3 months or every 6 months. I saw another endocrinologist who said "we do that all the time." Studies show that 2.5mg is as effective as 5mg on the usual schedule. My doses will be more frequent, 2-4 times/year. I'll post on how it goes.

It helps to have doctors who will work with you flexibly.

Also, I have been told I can wait 2-3 months after Evenity to start the Reclast. With Tymlos, I was told to take it right up until the first dose of Reclast.

Sorry to be off topic here though I suppose Reclast is relevant to getting off Prolia!

leeosteo.
I take the shot in the uppermost part of my thigh. I always sit down recommended because the low blood pressure starts within a minute of the injection. I only know because I dilligently used a blood pressure cuff for the first month. And because my blood pressure is already low.
The low blood pressure happens because pth causes vascular dilation. It begins to resolve as soon as it starts, but can take several hours. Don't plan on using the balance bars or anything else that requires balance for safety.
Some patients get headaches as a direct result of the vascular dilation. Two things counteract that mechanism fluids and salty foods. It's a great excuse to eat something a little salty.

I take vitamin k2 around two hours before I take calcium. I want the k in the bloodstream when the calcium arrives and I want the calcium in the bloodstream when the Forteo arrives.
This could be a flaw in my (over)thinking. And might not even be helpful.
I started with the injection in the morning and waited for a reaction. Never felt anything. In the beginning I'd pinch the skin and then let go, so as to avoid bruising. You might look to avoid any little surface vessel that might bleed, also to avoid those little polka dot bruises.
If you have any dizziness, best to take the injection at night to avoid any falling.
I never got a headach or any dizziness or anything negative.
These needles are so tiny. You'll laugh.
Oh, I hope you have luck. Let us know tomorrow.

I tolerated alendronate very well for 5 years. Now on shots 7 of Evenity. Any reason why I shouldn't go back on alendronate after evenity I stead of prolia or other thoughts.

Do you know of anyone who has successfully come off of Prolia? I have been on it for 2 years. I do have a history of vetebral compression fractures. I was not made aware of the issues of coming off it before I started. My endocrinologist wants me to be on it for at least another year. Dr. McCormack recommends only 2 years. I do wish to come off due to the issues that can arise, however, I am concerned about doing that very thing because of all those same issues. . I am very concerned. Any thoughts.

gently, thanks for the reply. May I ask how much you weigh? Are you eating something salty right before the shot?

I tolerated alendronate very well for 5 years. Now on shots 7 of Evenity. Any reason why I shouldn't go back on alendronate after evenity I stead of prolia or other thoughts.

I have been on Prolia almost 5 years when I went from osteopenia to osteoporosis. After 2 years my bone density went back yo osteopenia.
So my Endocrinologist has monitored me closely during those 5 years with multiple blood test and is now evaluating me to see if I can discontinue the Prolia. I will have a bone density test first. He did several X-Rays and had me se e a Rheumatologist who did other x-rays and results better than expected. According to recent studies if there’s significant improvement after 5 years one can come off and be given 1 Reclast in 6 months to help prevent rebound. So hopefully I will be one of the lucky ones to succeed in stopping. My Endocrinologist is really into close monitoring and I have been with him for over 10 years.

Can you site the recent studies that you mention about Prolia and 5 years? What type of test did you endocrinologist order for you? I am looking to go off Prolia and who appreciate information on the best way to go off of it. I am also looking for a endocrinologist who closely follows with bone turnover markers. I have been reading Dr. McCormack's book " GOOD BONES " on how to come off it. Also looking for first-hand experiences from people who have done it. I am very concerned.