Yes, your description - minus Depakote and substituting weight gain for weight loss -aligns with my long history of what was eventually diagnosed as Idiopathic Intercranial Hypertension. IIH led to a cerebrospinal fluid leak and surgical implantation of a ventriculoperitoneal shunt. IIH has become better known because of its association with the Mirena IUD (I do/did not have one) and the lawsuit against Bayer Corp. - and that raises the question for many women as to whether hormone therapy may be contributing to IIH and related symptoms. Another aspect to investigate might be mast cell activation and dysautonomia.